How to Use This Calculator
Pick your vial size (2, 5 or 10 mg, or type a custom amount), then enter how much bacteriostatic water you added, your daily dose in mcg and your syringe size. Click Calculate to see how many units and mL to draw, the concentration in mcg/mL, how many doses the vial holds and how many days it lasts at one dose a day. If the draw is too big for the syringe you chose, the calculator tells you.
What Is Sermorelin?
Sermorelin is the first 29 amino acids of human growth hormone releasing hormone (GHRH). That short piece is the smallest part of GHRH that still does the full job of telling the pituitary gland to release growth hormone.
Doses Used in Children with Growth Hormone Deficiency
Geref was first approved in 1990 as a 0.05 mg ampule for testing growth hormone release, and in 1997 as 0.5 mg and 1 mg vials for treatment. In children with growth hormone deficiency, treatment was 30 mcg per kg of body weight, injected under the skin once a day at bedtime, under specialist care. The maker stopped selling Geref in 2008, and in 2013 the FDA confirmed it was not withdrawn for reasons of safety or effectiveness. These details are shown as context, not as a dose to follow. (Sources: Prakash and Goa, BioDrugs 1999; Federal Register, 2013.)
Choosing the Water Volume and Syringe
Sermorelin doses are small, so a strong solution can make the draw tiny and hard to read. Adding more water makes each dose a bigger, easier-to-measure draw. The BAC Water Calculator helps you pick a water volume that gives a clean draw, and the Syringe Volume Calculator shows where that draw sits on each barrel size. For a dose based on body weight, use the Peptide Dosage Calculator, and to plan supply and cost, use the Peptide Vial Yield Calculator and the Peptide Cycle Cost Estimator.
Who Should Use This
Researchers working with lyophilised sermorelin who need to reconstitute a vial and turn a daily dose in mcg into syringe units.
What This Calculator Does
The Sermorelin Dosage Calculator turns a vial size, the bacteriostatic water added and a daily dose in mcg into the draw on a U-100 insulin syringe. It shows the units and mL to draw, the concentration, how many doses the vial holds and how many days it lasts at one dose a day.
Formula Used
Vial (mcg) = Vial size (mg) x 1,000Concentration (mcg/mL) = Vial (mcg) / BAC water (mL)Volume per dose (mL) = Daily dose (mcg) / ConcentrationUnits to draw = Volume (mL) x 100 (U-100 syringe)Doses per vial = FLOOR(Vial (mcg) / Daily dose)Days per vial = Doses per vial (one dose a day)Example Calculation
Limitations
This is a unit-conversion tool, not dosing guidance. It assumes the whole vial dissolves, a U-100 syringe and one dose a day, and it ignores dead space and draw loss. Very small draws, under about 5 units, are hard to measure accurately, so consider adding more water.
Frequently Asked Questions
Is sermorelin FDA-approved?
It was. Geref was approved in 1990 for testing and in 1997 for treating children with growth hormone deficiency. The maker stopped selling it in 2008, the FDA withdrew the approval in 2009, and in 2013 the FDA confirmed this was not for safety or effectiveness reasons.
How many units is 250 mcg of sermorelin?
It depends on the water in the vial. With 2 mg in 2 mL, 250 mcg is 25 units. With 5 mg in 2 mL, it is 10 units. With 10 mg in 2 mL, it is 5 units. All three are on a U-100 syringe.
Why is the dose in mcg and the vial in mg?
Sermorelin doses are small, so they are usually written in micrograms, while vials are sold in milligrams. 1 mg equals 1,000 mcg. The calculator converts the vial to micrograms for you.
How many days does a sermorelin vial last?
Turn the vial into micrograms, divide by your daily dose and round down. A 5 mg vial at 250 mcg a day lasts 20 days. A 2 mg vial at 300 mcg a day gives 6 full doses, with a little left over.
Does the syringe size change the number of units?
No. On any U-100 syringe, units are always mL x 100, so 0.1 mL is 10 units on a 1 mL, 0.5 mL or 0.3 mL barrel. A smaller syringe only changes how much it can hold.